South Dakota Innovative Partners has helped establish a diverse field of research and engineering-based companies across the region. Our focus lies in pharmocogenetic testing, information security, aquaculture, biochemical production and other research and technology-driven ventures. We have a unique collaboration with universities, health systems, corporations, economic development organizations, entrepreneurs and investors that allows us to be on the cutting-edge of identifying, evaluating and developing early-stage investment opportunities. We believe in the future. And we're ready to believe in you.

Our portfolio includes:

Tranzderm Solutions focuses on enhancing the delivery of cosmetics and pharmaceuticals into the skin for the treatment of dermatological diseases and other conditions. Tranzderm Solutions develops biocompatible, plant-based systems to successfully boost delivery of a wide range of active ingredients into the skin, significantly enhancing performance such as stability, solubility, penetration, retention and sustained release for multiple molecules, and further enhancing current cosmetic and pharmaceutical applications. Although these delivery systems serve as a platform technology for multiple markets, the company's strategic objective is to develop new treatments for dermatological diseases and other conditions such as melanoma, psoriasis, acne and aging by enhancing the efficiency of existing active ingredients.

Medgene Labs focuses on developing highly-specific and highly-sensitive instruments, assays and reagents that detect and help treat economically significant infectious diseases. Medgene's initial disease targets include porcine respiratory disease complex and prion diseases, which are not only economically significant to food animal health, but also have the potential to be zoonotic or transmissible to humans. One of the company's products, in partnership with Health Diagnostic Tools, collects airborne pathogens for the detection of infectious diseases. These pathogens are subsequently used in the mitigation and prevention of large disease outbreaks, reducing global economic and health threats.

Cyanosun Energy focuses on producing high value drop-in fuels and chemicals by converting carbon dioxide and sunlight using proprietary cyanobacteria systems. The current algae oil production model experiences significant challenges, such as harvesting the cells, extracting oil and refining the oil into a final product. Cyanosun's photosynthetic organisms and photo-bioreactor systems address these market challenges with economic efficiency, converting emissions of CO2 and low grade heat as waste products at ethanol plant and power plants into valuable co-products and reducing the carbon footprint of these facilities.

Prairie AquaTech produces aquaculture feed by converting plant-derived carbohydrates, such as soybeans and dried distillers' grain, into high-quality and highly-concentrated protein using the company's proprietary microbial-based processes. In addition to the economic benefits of the company's product over traditional fish meal, these proprietary processes also yield an exo-polysaccharide for increased efficiency in pellet binding and an immuno-stimulant for enhanced health in the aquaculture operations. The company produces an inexpensive, plant-derived protein-based feed that replaces expensive fish meal, while providing desirable growth rates and feed conversion efficiencies.

YouRx, in partnership with Avera Health, works with physicians around the world to personalize medicine for patients, beginning with children that have been diagnosed with a childhood behavioral disorder, such as attention deficit hyperactivity disorder or ADHD. YouRx analyzes a child's genetic profile to determine how the child will respond to drugs typically prescribed for ADHD, delivering a translational report to the physician that provides a personalized medical assessment of the child and supports the physician's treatment decision. YouRx' proprietary method and unique business model includes pharmacogenetic testing for other conditions, in addition to providing a diverse set of genotyping services.

Integrid Technologies provides alternative energy management products in distinct niche markets, such as measurement devices, power interface designs, battery health technologies, alternative energy harvest, load management, and use optimization. Integrid's objective is to fill a market need where there are open areas of development for technologies that integrate grid-connected and distributed alternative energy systems. Current market challenges include the cost of solar power, power conversion efficiency and advances in storage technology, which will be managed more effectively using Integrid's technologies.

NISM Snow is a First Dakota National Bank "Student Venture" that has designed an adapter to convert standard bikes into ski bikes that can ride downhill on snow at major ski resorts. NISM's ski bike adapter is unique in the market given its ease of use; removing the wheels of any standard bike and placing the adapters on the front and back hubs, allowing for dynamic positioning of the feet and creating a more realistic ride. The ski design is also proprietary, designed to ride well for quick transitions between turns, with internal springs that auto correct to changing snow levels, providing a more uniform ride. Similar to snowboarding, ski biking is being promoted at ski resorts around the world by industry associations such as the American Ski Bike Association and Ski-Bike World.